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Effect of high-dose Simvastatin on Brain Atrophy and Disability in Secondary Progressive Multiple Sclerosis (MS-STAT): A Randomised, Placebo-Controlled, Phase 2 Trial Lancet 383:2213-2221, Chataway, J.,et al, 2014 See this aricle in Pubmed Article Abstract High-dose simvastatin reduced the annualized rate of whole-brain atrophy compared with placebo, and was well tolerated and safe. These results support the advancement of this treatment to phase 3 testing.

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(click to filter results - removes previous filter) brain atrophy disability,neurological efficacy immunomodulation multiple sclerosis multiple sclerosis,treatment of neuroprotective agents safety simvastatin statin therapy treatment of neurologic disorder

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